IT Services Email IDUL and password Connect to UL network Academics Regular programs Continuing education Distance learning Course portal (ENA) University for seniors Human resources Employment opportunities PeopleSoft RH Campus life Library PEPS Rouge et Or Student residences Parking Emergency All ulaval.ca UL Directory UL Services Smoking electronic cigarettes kills large number of mouth cells Québec City, November 16, 2016—A large number of mouth cells exposed to e-cigarette vapor in the laboratory die within a few days, according to a study conducted by Université Laval researchers and published in the latest issue of Journal of Cellular Physiology.Dr. Mahmoud Rouabhia and his team at Université Laval’s Faculty of Dental Medicine came to this conclusion after exposing gingival epithelial cells to e-cigarette vapor.“Mouth epithelium is the body’s first line of defense against microbial infection,” Professor Rouabhia explains.

“This epithelium protects us against several microorganisms living in our mouths.” To simulate what happens in a person’s mouth while vaping, researchers placed epithelial cells in a small chamber containing a saliva-like liquid.e cigarette humiditéElectronic cigarette vapor was pumped into the chamber at a rate of two five-second “inhalations” per minute for 15 minutes a day.e cigarette hoover alObservations under the microscope showed that the percentage of dead or dying cells, which is about 2% in unexposed cell cultures, rose to 18%, 40%, and 53% after 1, 2,  and 3 days of exposure to e-cigarette vapor, respectively.e zigarette gebrauchsanweisung

“Contrary to what one might think, e-cigarette vapor isn’t just water,” explains Dr. Rouabhia.“Although it doesn’t contain tar compounds like regular cigarette smoke, it exposes mouth tissues and the respiratory tract to compounds produced by heating the vegetable glycerin, propylene glycol, and nicotine aromas in e-cigarette liquid.” The cumulative effects of this cell damage have not yet been documented, but they are worrying, according to Dr. Rouabhia, who is also a member of the Oral Ecology Research Group (GREB) at Université Laval: “Damage to the defensive barrier in the mouth can increase the risk of infection, inflammation, and gum disease.e cigarette joliet ilOver the longer term, it may also increase the risk of cancer.e cigarette kelapa gadingThis is what we will be investigating in the future.” In addition to Mahmoud Rouabhia, the study’s coauthors are: Hyun Jin Park, Andrew Zakrzewski, Witold Chmielewski, and Jamila Chakir (Université Laval); Abdelhabib Semlali (King Saud University).e cigarette irritability

-30- Information: Mahmoud Rouabhia Faculty of Dental Medicine Université Laval 418-656-2131 ext.16321 mahmoud.rouabhia@fmd.ulaval.ca Source: Jean-François Huppé Media Relations Université Laval 418-656-7785 jean-francois.huppe@dc.ulaval.ca All press releases Smoking electronic cigarettes kills large number of mouth cellsElectronic cigarettes represent an increasingly significant proportion of today's consumable tobacco products.E-cigarettes contain several chemicals which may promote oral diseases.The aim of this study was to investigate the effect of e-cigarette vapor on human gingival epithelial cells.Results show that e-cigarette vapor altered the morphology of cells from small cuboidal form to large undefined shapes.Both single and multiple exposures to e-cigarette vapor led to a bulky morphology with large faint nuclei and an enlarged cytoplasm.E-cigarette vapor also increased L-lactate dehydrogenase (LDH) activity in the targeted cells.

This activity was greater with repeated exposures.Furthermore, e-cigarette vapor increased apoptotic/necrotic epithelial cell percentages compared to that observed in the control.Epithelial cell apoptosis was confirmed by TUNEL assay showing that exposure to e-cigarette vapor increased apoptotic cell numbers, particularly after two and three exposures.This negative effect involved the caspase-3 pathway, the activity of which was greater with repeated exposure and which decreased following the use of caspase-3 inhibitor.The adverse effects of e-cigarette vapor on gingival epithelial cells may lead to dysregulated gingival cell function and result in oral disease.© 2016 Wiley Periodicals, Inc.Continue reading full articleThat conclusion is emerging from a cloud of uncertainty and misleading suggestions that electronic cigarettes offer a safe alternative to traditional cigarettes.New studies make it clear that even though e-cigs don’t contain tobacco, they still pose an array of dangers to your health.

Researchers at the University of Rochester Medical Center say their study was the first to examine the effect of e-cigarettes on oral health at the cellular level.They concluded that e-cigarettes are as damaging to the gums and teeth as conventional cigarettes.“We showed that when the vapors from an e-cigarette are burned, it causes cells to release inflammatory proteins, which in turn aggravate stress within cells, resulting in damage that could lead to various oral diseases,” said Irfan Rahman, Ph.D., a professor of environmental medicine and lead author of the study.“How much and how often someone is smoking e-cigarettes will determine the extent of damage to the gums and oral cavity.” Another study out of Canada drew similar conclusions about the effects of e-cigs on oral cells.“The adverse effects of e-cigarette vapor on gingival epithelial cells may lead to dysregulated gingival cell function and result in oral disease,” wrote the authors, led by Mahmoud Rouabhia, Ph.D., of the Universite Laval, Quebec.

E-cigarettes convert liquids containing nicotine into vapor that smokers inhale.They have been widely marketed as safe alternatives to smoking.Providence and other health experts disagree.Meera Jain, M.D., medical director of the Providence Tobacco Cessation and Prevention Program, called the claims of e-cigarette marketers “magical thinking.” “The next time you find yourself or someone else wishing on a genie,” she wrote, “remind them that, when it comes to smoking, the only safe magic is to quit.” The U.S.Food and Drug Administration said this spring it will treat e-cigarettes the same as it treats regular cigarettes, requiring manufacturers to carry warning labels and limit sales to minors.“We have more to do to help protect Americans from the dangers of tobacco and nicotine, especially our youth,” said U.S.Secretary of Health and Human Services Sylvia Burwell.Nevertheless, the market for e-cigarettes has exploded.Since they were introduced in 2004, they have fueled a market that was valued at $2.5 billion in 2014, according to The Tobacco Atlas.