MEDICAL RESEARCH For less toxic e-cigarettes, skip the strawberry By Lisa Rapaport Published October 06, 2016 0 0 When it comes to e-cigarette safety, flavorings added to the liquid nicotine burned in the devices may influence how much the fumes lead to health problems, a recent study suggests.Researchers tested vapor released by a variety of devices filled with some popular e-cigarette flavors - tobacco, pina colada, menthol, coffee and strawberry - to compare levels of chemicals known to cause inflammation and cell damage.They also looked at how much these chemicals appeared in tobacco smoke and in smoke-free air.More on this... Are e-cig injuries exploding upward?E-cigarette users view smoke-free areas as okay for vaping E-cigarette makers rush new products to market ahead of US rules As expected, cigarette smoke was more toxic than fumes from e-cigarettes, said senior study author Maciej Goniewicz of Roswell Park Cancer Institute in Buffalo, New York.

E-cigarettes, however, had more toxic chemicals than smoke-free air, especially when the devices had higher power or voltage and when used with flavored liquid nicotine."We found that strawberry-flavored product was the most toxic among all liquids we tested," Goniewicz added by email.The researchers exposed human lung cells in a dish to smoke, e-cigarette vapors and air.The cells reacted most strongly to smoke, by reducing their metabolic activity and increasing output of inflammation-related chemicals.Similar, but not as strong, reactions were seen with e-cigarette vapor, compared to no change with plain air.Past research has found that higher-voltage e-cigarettes produce a bigger nicotine jolt, but may also increase levels of dangerous chemicals like formaldehyde."Our findings raise some concerns about the safety of additives used in e-cigarettes," Goniewicz said."If an e-cigarette user experiences any side effects, for example cough or chest pain, he or she should consider changing the flavorings in the product and operating their device in lower-power settings."

tobacco companies are all developing e-cigarettes.The battery-powered gadgets feature a glowing tip and a heating element that turns liquid nicotine and flavorings into a cloud of vapor that users inhale.An international review of published research by the Cochrane Database of Systematic Reviews last month concluded that the devices could help smokers quit but said much of the existing evidence on e-cigarette safety was thin.e cigarette puyallup waThe current study doesn't offer a complete picture of e-cigarette safety or address the potential for health problems to emerge after long-term use, the authors note.e cigarette sceauxBut it does suggest flavors may have an outsize impact on safety, the authors conclude in the journal Tobacco Control.e cigarette reaction

A separate study in the journal looked at cinnamaldehyde, a chemical added to liquid nicotine to create cinnamon flavors.In lab tests of fluids from 39 refill cartridges of liquid nicotine, 20 contained enough cinnamaldehyde to damage cells, the study found.This included products labeled as cinnamon flavored as well as a variety of sweet and fruity mixtures.e cigarette truvapeHere, too, the level of toxicity appeared greater with higher voltage devices.e cigarette smith haven mall"We previously showed that cinnamaldehyde was highly toxic when tested in vitro with various types of cells," said senior study author Prue Talbot of the University of California, Riverside.e cigarette store in kolkata"In the new study, we further showed that cinnamaldehyde is much more widely distributed in e-cigarette products than originally thought and it appears in many sweet and fruity flavors, which are among the most popular," Talbot added by email.

Flavorings, higher voltage increase toxicity of e-cigs Date: September 19, 2016 Source: Summary: Several flavorings added to electronic cigarettes impact the toxicity of the devices, say researchers, adding that, among the tested flavors, strawberry was the most toxic.The researchers also confirmed an earlier finding that increasing the battery output voltage of these devices significantly increases toxicity.Share: Close Roswell Park Cancer Institute scientists report that several flavorings added to electronic cigarettes impact the toxicity of the devices and that, among the tested flavors, strawberry was the most toxic.The study has been published online ahead of print in the journal Tobacco Control."Although many of the flavorings used in e-cigarette liquids have been certified as safe for eating, little is known about their effects when heated and inhaled in e-cigarettes," says the study's senior author, Maciej Goniewicz, PhD, PharmD, Assistant Professor of Oncology in the Department of Health Behavior at Roswell Park.

"This study suggests that various characteristics of e-cigarettes, including any flavorings, may induce inhalation toxicity and therefore, caution should be used with these products until more comprehensive studies are performed."In this study, researchers exposed bronchial cells to aerosol generated from several variable-voltage e-cigarettes.They analyzed cell viability and activity as well as the release of inflammatory mediators.They evaluated six types of e-cigarette devices filled with liquids of different flavors -- tobacco, pina colada, menthol, coffee and strawberry -- at several battery output voltages.Their findings suggest that the power of the e-cigarette device, as well as the addition of any flavorings, significantly affect the toxicity of e-cigarette aerosol, with strawberry flavorings being the most toxic to users."Our study demonstrates that e-cigarette products differ significantly in the degree of their cellular toxicity to bronchial epithelial cells," adds Dr. Goniewicz.