2006 Jun;95(6):1308-17.Hazekamp A1, Ruhaak R, Zuurman L, van Gerven J, Verpoorte R.Author information1Division of Pharmacognosy, Institute of Biology, Leiden University, Leiden, The Netherlands.AbstractWhat is currently needed for optimal use of medicinal cannabinoids is a feasible, nonsmoked, rapid-onset delivery system.Cannabis "vaporization" is a technique aimed at suppressing irritating respiratory toxins by heating cannabis to a temperature where active cannabinoid vapors form, but below the point of combustion where smoke and associated toxins are produced.The goal of this study was to evaluate the performance of the Volcano vaporizer in terms of reproducible delivery of the bioactive cannabinoid tetrahydrocannabinol (THC) by using pure cannabinoid preparations, so that it could be used in a clinical trial.By changing parameters such as temperature setting, type of evaporation sample and balloon volume, the vaporization of THC was systematically improved to its maximum, while preventing the formation of breakdown products of THC, such as cannabinol or delta-8-THC.

Inter- and intra-device variability was tested as well as relationship between loaded- and delivered dose.It was found that an average of about 54% of loaded THC was delivered into the balloon of the vaporizer, in a reproducible manner.When the vaporizer was used for clinical administration of inhaled THC, it was found that on average 35% of inhaled THC was directly exhaled again.Our results show that with the Volcano a safe and effective cannabinoid delivery system seems to be available to patients.The final pulmonal uptake of THC is comparable to the smoking of cannabis, while avoiding the respiratory disadvantages of smoking.(c)and the American Pharmacists AssociationPMID: 16637053 DOI: 10.1002/jps.20574 [Indexed for MEDLINE] Publication typesComparative StudyEvaluation StudiesMeSH termsAdministration, InhalationAerosolsCannabis/chemistryClinical Trials as TopicDose-Response Relationship, DrugDronabinol/administration & dosage*Dronabinol/metabolismDronabinol/pharmacology*Drug Delivery Systems*Evaluation Studies as TopicHot TemperatureHumansLung/drug effectsLung/metabolism*Nebulizers and Vaporizers*Nuclear Magnetic Resonance, BiomolecularReproducibility of ResultsSubstancesAerosolsDronabinolFull Text SourcesElsevier ScienceWileyOther Literature SourcesCited by Patents in - The LensMiscellaneousdelta 9-Tetrahydrocannabinol - Hazardous Substances Data Bank

Home Products My Account Contact Us Warranty Featured Products 11414 Alphabetical Price (High to Low) Price (Low to High) Most Recent Baker Glass Fitting Baker Tabletop Vaporizer by VaporBlunt, compact and fast heating with a tempeture adjusting knob and just one power button.(1) 6 Pack Bullet Holder 6 Pack Bullet Holder for Pinnacle products (Bullets Included) Palm 1.0 This handheld and compact unit features an all-glass air path that ensures the cleanest and best tasting vapor possible.personal vaporizer adalah(1) Palm 2.0 The Palm 2.0 now smaller than the Palm 1.0 as well as a smoother better hit with the improved mouthpiece and screen.vaporizer atmos rawVaporblunt 2.0 The VaporBLUNT 2.0 Vaporizer is built to work for both dried blends and essential oils at any altitude; along with a sleek design that is half the size of its predecessor, the Original Vapor Blunt.vaporizer kopen arnhem

(1) Pinnacle Pro The Pinnacle Pro is our portable dry herb and essential oil vaporizer which features five different heat settings for the best vaporizing experience possible.(4) Pinnacle The pinnacle vaporizer from VaporBlunt, a portable vaporizer with 2 heat settings made for both dried herbs and essential oils.(2) Pinnacle Pro DLX The pinnacle pro vaporizer from VaporBlunt (2) Pinnacle DLX The Pinnacle vaporizer DLX kit is the Pinnacle portable vaporizer built for both dried herbs and essential oils with a unquie water tool for a cleaner taste.bug vaporizerVaporblunt 2.0 DLX The VaporBLUNT 2.0 Vaporize is built to work for both dried blends and essential oils and it is now availible in the DLX kit that also includes a water tool.bikin vaporizerChandelier Water Tool Attachment Water tool kit with chandelier perk for Original Vaporblunt and VB 2.0 Simba Frit Watertool Attachment 65mm Tube approximately  8 1/2" tall with Lazy boy mouthpiece and 18mm German Dewar Joint 14.4 mm Micro-shower Water Tool Attachment The 14.4 mm microshower is a portable water tool attachment used with the Pinnacle or any 14.4 mm male adapter, out on the martket.vaporizer bahrain

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Warm Steam Vaporizer Tabletop Humidifier - Blue Adds moisture to the air for easier breathing and sleep Relieves nasal congestion, cough, sinus irritation, and dry skin Alternative to over the counter cough and cold medicine A Feel Good FavoriteGet relief from Cold and Flu Symptoms and bring Wellness to your entire Family with a Crane Warm Steam Vaporizer.Featuring a sleek design, Crane’s Vaporizers provide up to 24 hours of soothing, bacteria-free moisture to help relieve the effects of dryness and congestion, helping you and your Family to breathe easy and sleep through the night peacefully.Bacteria-Free Warm Mist increases air moisture for easier breathing and a good night’s sleep Relieves cough, cold, and flu symptoms, nasal congestion, dry cough, sinus irritation, nose bleeds, and dry skin and hair Recommended non-medicated alternative to over the counter cough and cold medicine Removable 1 gallon, dishwasher safe water tank runs whisper quiet for up to 15 hours Effectively humidifies small and medium rooms Auto-Off function activates when water tank is empty Steam Guard with Integrated Steam Diffuser Can be used with Steam Medications Power: 300W FDA Registered, BPA Free Click here for more information on Electronic Recycling Programs Info & Guides Full Product Manual Warranty You will need Adobe® Acrobat® Reader to view PDF documents.